Title : Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol.

Pub. Date : 1987 Jul 15

PMID : 3110162






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 UDPGTr-3 and a related phenobarbital-inducible form of UDP-glucuronosyltransferase (designated UDPGTr-2) were both expressed in COS cells and their capacities to glucuronidate 13 commonly used substrates were analyzed. Phenobarbital UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus
2 These data show that at least two forms of UDP-glucuronosyltransferase found predominantly in the liver have evolved to glucuronidate the same endogenous steroid substrates and that the phenobarbital-inducible form also has some activity towards foreign compounds. Phenobarbital UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus