Pub. Date : 2020 Jan 15
PMID : 31095840
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22. | n-glycans | CD22 molecule | Homo sapiens |
| 2 | Here we have characterised the dynamic recognition of complex-type N-glycans by human CD22 by means of orthogonal approaches including NMR spectroscopy, computational methods and biophysical assays. | n-glycans | CD22 molecule | Homo sapiens |
| 3 | We provide new molecular insights into the binding mode of sialoglycans in complex with h-CD22, highlighting the role of the sialic acid galactose moieties in the recognition process, elucidating the conformational behaviour of complex-type N-glycans bound to Siglec-2 and dissecting the formation of CD22 homo-oligomers on the B-cell surface. | n-glycans | CD22 molecule | Homo sapiens |