Title : DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer.

Pub. Date : 2019 Jul 1

PMID : 31088836






2 Functional Relationships(s)
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1 To improve the efficacy of epigenetic therapy, we hypothesized that the addition of alpha-difluoromethylornithine (DFMO), an ornithine decarboxylase inhibitor, may further decrease immunosuppressive cell populations improving outcome. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
2 To improve the efficacy of epigenetic therapy, we hypothesized that the addition of alpha-difluoromethylornithine (DFMO), an ornithine decarboxylase inhibitor, may further decrease immunosuppressive cell populations improving outcome. Eflornithine ornithine decarboxylase, structural 1 Mus musculus