Title : Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritis.

Pub. Date : 2019 May

PMID : 31076346






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Blockade of CD39/CD73 or adenosine receptors has significantly abrogated the suppressive ability of GMSC in vitro and therapeutic effect of GMSC on bone erosion during CIA in vivo. gmsc 5'-nucleotidase ecto Homo sapiens
2 Blockade of CD39/CD73 or adenosine receptors has significantly abrogated the suppressive ability of GMSC in vitro and therapeutic effect of GMSC on bone erosion during CIA in vivo. gmsc 5'-nucleotidase ecto Homo sapiens
3 INTERPRETATION: GMSC inhibit osteoclast formation in vitro and in vivo partially via CD39-CD73-adenosine signals. gmsc 5'-nucleotidase ecto Homo sapiens