Pub. Date : 2019
PMID : 31071106
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Photolabeling experiments showed that sevoflurane directly bound to Rap1. | Sevoflurane | RAS-related protein 1a | Mus musculus |
2 | Mutagenesis analysis demonstrated that the sevoflurane binding site affected Rap1 activation and macrophage phagocytosis. | Sevoflurane | RAS-related protein 1a | Mus musculus |
3 | Our study showed for the first time that sevoflurane served as a novel small GTPase Rap1 inhibitor. | Sevoflurane | RAS-related protein 1a | Mus musculus |
4 | The sevoflurane binding site was located outside the known Rap1 functional sites, indicating the discovery of a new functional site on Rap1 and this site would serve as a pocket for the development of novel Rap1 inhibitors. | Sevoflurane | RAS-related protein 1a | Mus musculus |
5 | The sevoflurane binding site was located outside the known Rap1 functional sites, indicating the discovery of a new functional site on Rap1 and this site would serve as a pocket for the development of novel Rap1 inhibitors. | Sevoflurane | RAS-related protein 1a | Mus musculus |
6 | The sevoflurane binding site was located outside the known Rap1 functional sites, indicating the discovery of a new functional site on Rap1 and this site would serve as a pocket for the development of novel Rap1 inhibitors. | Sevoflurane | RAS-related protein 1a | Mus musculus |