Title : Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response.

Pub. Date : 2019 Sep

PMID : 31063779






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LCCLs with inactivating mutations in TSC1 and TSC2 were sensitive to the mammalian target of rapamycin inhibitor rapamycin, and cells with inactivating mutations in TP53 were sensitive to the Aurora kinase A inhibitor alisertib. MLN 8237 tumor protein p53 Homo sapiens