Title : Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors.

Pub. Date : 2019 Apr 1

PMID : 31057732






1 Functional Relationships(s)
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1 Biological evaluation on clinical bacterial isolates, harbouring either the NDM-1 or VIM-2 metallo-beta-lactamase, showed a clear relationship between the zinc chelator strength and restoration of meropenem activity. Meropenem vimentin 2, pseudogene Homo sapiens