Title : The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice.

Pub. Date : 1987 Mar 15

PMID : 3105541






2 Functional Relationships(s)
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1 The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice. Methoxsalen cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus
2 Methoxsalen, a potent suicide inhibitor of cytochrome P-450 that can be used in humans, might be of value for the prevention of hepatitis in subjects with carbon tetrachloride poisoning. Methoxsalen cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus