Title : Macrophage derived TNFα promotes hepatic reprogramming to Warburg-like metabolism.

Pub. Date : 2019 Sep

PMID : 31053970






1 Functional Relationships(s)
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1 Following injection with polyinosinic:polycytidylic acid, a mimic of viral infection, a robust hepatic innate immune response could be seen involving the TNFalpha pathway at 2 h. Repeated doses led to the adoption of Warburg-like metabolism in the liver as determined by in vivo metabolic imaging, expression analyses, and metabolomics. Poly C tumor necrosis factor Homo sapiens