Title : Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner.

Pub. Date : 2019 Sep

PMID : 31044513






3 Functional Relationships(s)
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1 Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner. Hyaluronic Acid TNF alpha induced protein 6 Homo sapiens
2 Besides, macrophages primed with high-molecular weight hyaluronan and inoculated in human breast cancer xenograft tumor increased blood vessel formation and diminished TSG-6 levels. Hyaluronic Acid TNF alpha induced protein 6 Homo sapiens
3 Taken together, these results indicate that the effect of high-molecular weight hyaluronan as an inductor of the angiogenic behavior of macrophages in breast tumor context is in part consequence of the presence of TSG-6. Hyaluronic Acid TNF alpha induced protein 6 Homo sapiens