Title : A study of sirolimus and mTOR kinase inhibitor in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease.

Pub. Date : 2019 Jul 1

PMID : 31042058






1 Functional Relationships(s)
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1 Both sirolimus and torin2 decreased phosphorylated S6 protein, phosphorylated eukaryotic translation initiation factor 4E-binding protein 1, phosphorylated Akt, and proliferation in Pkd1RC/RC kidneys. Sirolimus thymoma viral proto-oncogene 1 Mus musculus