Title : Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.

Pub. Date : 2019 Jun 20

PMID : 31031142






4 Functional Relationships(s)
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1 We show that IP6 and inositol pentakisphosphate 2-kinase (IPPK) are required for necroptosis as IPPK deletion ablated IP6 production and inhibited necroptosis. Phytic Acid inositol-pentakisphosphate 2-kinase Homo sapiens
2 We show that IP6 and inositol pentakisphosphate 2-kinase (IPPK) are required for necroptosis as IPPK deletion ablated IP6 production and inhibited necroptosis. Phytic Acid inositol-pentakisphosphate 2-kinase Homo sapiens
3 We show that IP6 and inositol pentakisphosphate 2-kinase (IPPK) are required for necroptosis as IPPK deletion ablated IP6 production and inhibited necroptosis. Phytic Acid inositol-pentakisphosphate 2-kinase Homo sapiens
4 We show that IP6 and inositol pentakisphosphate 2-kinase (IPPK) are required for necroptosis as IPPK deletion ablated IP6 production and inhibited necroptosis. Phytic Acid inositol-pentakisphosphate 2-kinase Homo sapiens