Title : Thimerosal induces endothelium-dependent vascular smooth muscle relaxations by interacting with thiol groups. Relaxations are likely to be mediated by endothelium-derived relaxing factor (EDRF).

Pub. Date : 1986 Dec

PMID : 3102978






1 Functional Relationships(s)
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1 Endothelium-dependent relaxations induced by larger concentrations of thimerosal, as well as relaxations produced by acetylcholine, were inhibited by the antioxidant and lipoxygenase inhibitor nordihydroguaiaretic acid, by haemoglobin, and by the inhibitor of soluble guanylate cyclase methylene blue. Masoprocol polyunsaturated fatty acid lipoxygenase ALOX15 Oryctolagus cuniculus