Title : Ziyuglycoside II induces caspases-dependent and caspases-independent apoptosis in human colon cancer cells.

Pub. Date : 2019 Sep

PMID : 31029785






1 Functional Relationships(s)
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1 Apoptosis caused by p53 phosphorylation following ziyuglycoside II treatment in HCT116 cells involved activation of caspases, increased expression of BAX, mitochondrial cytochrome c and apoptosis inducing factor (AIF) release, while BCL-2 became down-regulated. ziyuglycoside II BCL2 associated X, apoptosis regulator Homo sapiens