Title : Genetic Deficiency and Biochemical Inhibition of ITK Affect Human Th17, Treg, and Innate Lymphoid Cells.

Pub. Date : 2019 May

PMID : 31025232






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An irreversible inhibitor of ITK, ibrutinib, blocked ex vivo Th17 generation and IL-17A production, conversely augmented FOXP3 expression only at low doses in Treg cultures. ibrutinib IL2 inducible T cell kinase Homo sapiens