Pub. Date : 2020 Jan
PMID : 31022458
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | There is a unique in vivo interplay involving the mechanism of inactivation of acetylcholinesterase (AChE) by toxic organophosphorus (OP) compounds and the restoration of AChE activity by oxime antidotes. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | OP compounds form covalent adducts to this critical enzyme target and oximes are introduced to directly displace the OP from AChE. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |