Title : Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice.

Pub. Date : 2019 Oct

PMID : 31000769






2 Functional Relationships(s)
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1 In BV2 cells and primary cortical astrocytes, NTZ stimulated autophagy and promoted Abeta clearance by inhibiting both PI3K/AKT/mTOR/ULK1 and NQO1/mTOR/ULK1 signaling pathways; NTZ treatment attenuated LPS-induced inflammation by inhibiting PI3K/AKT/IkappaB/NFkappaB signaling. nitazoxanide thymoma viral proto-oncogene 1 Mus musculus
2 In BV2 cells and primary cortical astrocytes, NTZ stimulated autophagy and promoted Abeta clearance by inhibiting both PI3K/AKT/mTOR/ULK1 and NQO1/mTOR/ULK1 signaling pathways; NTZ treatment attenuated LPS-induced inflammation by inhibiting PI3K/AKT/IkappaB/NFkappaB signaling. nitazoxanide thymoma viral proto-oncogene 1 Mus musculus