Title : Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study.

Pub. Date : 2019 May

PMID : 31000417






1 Functional Relationships(s)
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1 BACKGROUND: The polymorphic CYP2D6 enzyme metabolises the antipsychotic drugs risperidone and aripiprazole to their active metabolites, 9OH-risperidone and dehydroaripiprazole. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens