Pub. Date : 2019 Nov 1
PMID : 30990221
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Tamoxifen increased ESR2-mutant TP53 interaction leading to reactivation of TP73 and apoptosis. | Tamoxifen | tumor protein p53 | Homo sapiens |
2 | Our study suggests that ESR2-mutant TP53 combination prognosticates survival in TNBC revealing a novel strategy to stratify TNBC for therapeutic intervention potentially by repurposing tamoxifen. | Tamoxifen | tumor protein p53 | Homo sapiens |