Title : S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway.

Pub. Date : 2019 Apr 15

PMID : 30988280






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 H2O2 activated AMPK, which then phosphorylated SIRT1 and inhibited its deacetylation activity toward p53 in A549 cells or FOXO1 in NCI-H1299 cells. Hydrogen Peroxide tumor protein p53 Homo sapiens