Title : Acromegaly due to a growth hormone-releasing hormone-secreting bronchial carcinoid tumor: further information on the abnormal responsiveness of the somatotroph cells and their recovery after successful treatment.

Pub. Date : 1987 Feb

PMID : 3098773






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Two weeks after removal of the carcinoid tumor, TRH induced GH secretion (250%) when the IR-GHRH level was undetectable and somatomedin-C was within normal limits. ghrh thyrotropin releasing hormone Homo sapiens
2 When acromegaly and abnormal GH responsiveness are induced by a GHRH-secreting tumor, the increases in plasma GH after TRH, glucose, and insulin administration are not mediated by GHRH. ghrh thyrotropin releasing hormone Homo sapiens
3 After removal of the GHRH-secreting tumor, persistent paradoxical GH response to TRH does not require abnormally high IR-GHRH levels and does not preclude complete recovery. ghrh thyrotropin releasing hormone Homo sapiens