Title : Plasma membrane G protein-coupled estrogen receptor 1 (GPER) mediates rapid estradiol facilitation of sexual receptivity through the orphanin-FQ-ORL-1 system in estradiol primed female rats.

Pub. Date : 2019 Jun

PMID : 30981690






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ARH infusion of non-esterified 17beta-estradiol (E2) 47.5 h after 17beta-estradiol benzoate (2 mug EB) priming deactivates MPN MOP and rapidly facilitates lordosis within 30 min via activation of GPER. Estradiol G protein-coupled estrogen receptor 1 Rattus norvegicus
2 These data indicate that membrane GPER mediates the E2/E-Biotin facilitation of lordosis by inducing OFQ/N neurotransmission, which inhibits beta-END neurotransmission to reduce MPN MOP activation. Estradiol G protein-coupled estrogen receptor 1 Rattus norvegicus