Title : Interpreting the Dynamics of Binding Interactions of snRNA and U1A Using a Coarse-Grained Model.

Pub. Date : 2019 May 7

PMID : 30975455






1 Functional Relationships(s)
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1 The results reveal that the first and third loops and the C-terminal helix regions of the U1A domain undergo a significant loss of flexibility upon the RNA binding due to the forming of mostly electrostatic and hydrogen bond interactions with RNA 5" stem and loop. Hydrogen small nuclear ribonucleoprotein polypeptide A Homo sapiens