Title : The PI3K inhibitor copanlisib synergizes with sorafenib to induce cell death in hepatocellular carcinoma.

Pub. Date : 2019

PMID : 30962952






1 Functional Relationships(s)
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Protein Name
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1 Copanlisib strongly reduced cell viability and colony formation in different native and sorafenib-resistant HCC cell lines by affecting cyclin D1/CDK4/6 signaling and causing cell cycle arrest. Sorafenib cyclin dependent kinase 4 Homo sapiens