Pub. Date : 2019 Jul
PMID : 30959153
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using vesicular transport assay with recombinant human MRP2, MRP3, MRP4, MDR1 and BCRP, we first identified that TG, AG, EtioG, and DHTG were primarily substrates of MRP2 and MRP3, although lower levels of transport were also observed with MDR1 and BCRP vesicles. | androsterone glucuronide | ATP binding cassette subfamily C member 3 | Homo sapiens |
| 2 | Using vesicular transport assay with recombinant human MRP2, MRP3, MRP4, MDR1 and BCRP, we first identified that TG, AG, EtioG, and DHTG were primarily substrates of MRP2 and MRP3, although lower levels of transport were also observed with MDR1 and BCRP vesicles. | androsterone glucuronide | ATP binding cassette subfamily C member 3 | Homo sapiens |
| 3 | The glucuronides of inactive androgens, AG and EtioG were preferentially transported by MRP3, whereas the glucuronides of active androgens, TG and DHTG were mainly transported by MRP2 in liver. | androsterone glucuronide | ATP binding cassette subfamily C member 3 | Homo sapiens |