Title : Bisphenol-A exposure induced neurotoxicity in glutamatergic neurons derived from human embryonic stem cells.

Pub. Date : 2019 Jun

PMID : 30953815






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Studies have shown that BPA interferes with the development and functions of the brain, but little is known about the effects of BPA on human glutamatergic neurons (hGNs) at the molecular and cellular levels. bisphenol A glucosamine (N-acetyl)-6-sulfatase Homo sapiens
2 We investigated the impact of chronic exposure to BPA to hGNs derived from human embryonic stem cells (hESCs). bisphenol A glucosamine (N-acetyl)-6-sulfatase Homo sapiens
3 The results showed that chronic exposure of different concentrations of BPA (0, 0.1, 1.0 and 10 muM) to hGNs for 14 days reduced neurite outgrowth in a concentration-dependent manner. bisphenol A glucosamine (N-acetyl)-6-sulfatase Homo sapiens