Title : Sesamin Catechol Glucuronides Exert Anti-inflammatory Effects by Suppressing Interferon β and Inducible Nitric Oxide Synthase Expression through Deconjugation in Macrophage-like J774.1 Cells.

Pub. Date : 2019 Jul 10

PMID : 30951310






3 Functional Relationships(s)
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1 The inhibitory effects of SC1 glucuronides were time-dependently enhanced, associated with the intracellular accumulation of SC1 and the methylated form. Glucuronides spinal cord QTL 1 Mus musculus
2 The inhibitory effects of SC1 glucuronides were time-dependently enhanced, associated with the intracellular accumulation of SC1 and the methylated form. Glucuronides spinal cord QTL 1 Mus musculus
3 Our results suggest that SC1 glucuronides exert the anti-inflammatory effects by inhibiting the IFN-beta/iNOS signaling through macrophage-mediated deconjugation. Glucuronides spinal cord QTL 1 Mus musculus