Title : Learning and memory deficits and alzheimer's disease-like changes in mice after chronic exposure to microcystin-LR.

Pub. Date : 2019 Jul 5

PMID : 30947040






1 Functional Relationships(s)
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1 Following prolonged exposure, MC-LR significantly upregulated the ratio of proBDNF to BDNF by downregulating the tPA levels, thereby activating downstream signaling pathways to improve the expression of p-JNK, and c-Jun while to inhibit the expression of p-Creb and p-PKC. cyanoginosin LR brain derived neurotrophic factor Mus musculus