Title : Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome.

Pub. Date : 2019 Apr 3

PMID : 30944389






1 Functional Relationships(s)
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1 A mechanistic study revealed that GlcN inhibited the expression of NLRP3 and IL-1beta precursor by reducing reactive oxygen species generation and NF-kappaB activation in lipopolysaccharide-activated macrophages. oxygen species NLR family pyrin domain containing 3 Homo sapiens