Title : Interaction of Anticancer Drugs with Human Organic Anion Transporter hOAT4.

Pub. Date : 2019

PMID : 30941173






3 Functional Relationships(s)
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1 The IC50 values for epirubicin hydrochloride and dabrafenib mesylate were 5.24+-0.95 muM and 8.30+-3.30 muM, respectively. Epirubicin latexin Homo sapiens
2 The IC50 values for epirubicin hydrochloride and dabrafenib mesylate were 5.24+-0.95 muM and 8.30+-3.30 muM, respectively. Epirubicin latexin Homo sapiens
3 Dixon plot analysis revealed that inhibition by epirubicin hydrochloride was noncompetitive with a Ki = 3 muM whereas inhibition by dabrafenib mesylate was competitive with a Ki = 4.26 muM. Epirubicin latexin Homo sapiens