Title : Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.

Pub. Date : 2019 May 15

PMID : 30940658






3 Functional Relationships(s)
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1 Temozolomide Treatment Induces lncRNA MALAT1 in an NF-kappaB and p53 Codependent Manner in Glioblastoma. Temozolomide tumor protein p53 Homo sapiens
2 Temozolomide treatment inhibited p50 recruitment to its cognate element as a function of Ser329 phosphorylation while concomitantly increasing p53 recruitment. Temozolomide tumor protein p53 Homo sapiens
3 Moreover, luciferase reporter studies demonstrated that both kappaB and p53 cis-elements were required for efficient transactivation in response to temozolomide. Temozolomide tumor protein p53 Homo sapiens