Title : Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor.

Pub. Date : 2019 Aug 1

PMID : 30940656






2 Functional Relationships(s)
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1 Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor. Auranofin tumor protein p53 Homo sapiens
2 RESULTS: Both in the mouse model of intestinal injury and in the human nonmalignant colon organoid culture, auranofin pretreatment prevented radiation toxicity and improved survival with the activation of p53/p21-mediated reversible cell-cycle arrest. Auranofin tumor protein p53 Homo sapiens