Title : Stimulation of β-adrenoceptors up-regulates cardiac expression of galectin-3 and BIM through the Hippo signalling pathway.

Pub. Date : 2019 Jul

PMID : 30932177






3 Functional Relationships(s)
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1 KEY RESULTS: Isoprenaline treatment up-regulated expression of galectin-3 and BIM, and this was inhibited by non-selective or selective beta-adrenoceptor antagonists (by 60-70%). Isoproterenol lectin, galactose binding, soluble 3 Mus musculus
2 Isoprenaline-induced up-regulation of galectin-3 and BIM was attenuated by Mst1 inactivation, but isoprenaline-induced galectin-3 expression was exaggerated by transgenic Mst1 activation. Isoproterenol lectin, galactose binding, soluble 3 Mus musculus
3 Isoprenaline-induced up-regulation of galectin-3 and BIM was attenuated by Mst1 inactivation, but isoprenaline-induced galectin-3 expression was exaggerated by transgenic Mst1 activation. Isoproterenol lectin, galactose binding, soluble 3 Mus musculus