Title : High affinity of AS1411 toward copper; its application in a sensitive aptasensor for copper detection.

Pub. Date : 2019 Jun 15

PMID : 30926271






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 AS1411 is a 26-mer G-rich DNA aptamer which has been broadly employed in the field of targeted drug delivery, due to its capability to bind to nucleolin protein on the surface of cancer cells. AGRO 100 nucleolin Homo sapiens
2 In this work, it has been shown for the first time that in addition to nucleolin, AS1411 aptamer could bind to copper ions (Cu2+) with high affinity and selectivity, affecting AS1411 usage in drug delivery systems as a targeting agent. AGRO 100 nucleolin Homo sapiens