Pub. Date : 2019 Apr 18
PMID : 30913878
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Role of Disulfide Bonds and Topological Frustration in the Kinetic Partitioning of Lysozyme Folding Pathways. | Disulfides | lysozyme | Homo sapiens | ||
| 2 | Lysozyme has four disulfide bonds and is widely studied for its antibacterial properties. | Disulfides | lysozyme | Homo sapiens | ||
| 3 | Using a coarse-grained protein model and simulations, we show that two out of the four disulfide bonds, which are present in the alpha-domain of lysozyme, are responsible for the slow folding pathway. | Disulfides | lysozyme | Homo sapiens | ||
| 4 | These results show that lysozyme also serves as a very good model system to probe the role of disulfide bonds and topological frustration in protein folding. | Disulfides | lysozyme | Homo sapiens | ||