Title : Prolactin modulates steroidogenesis by rat granulosa cells: I. Effects on progesterone.

Pub. Date : 1986 Aug

PMID : 3091106






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Prolactin significantly enhanced the stimulatory effects of testosterone or FSH alone on cells from both HPX and proestrous rats. Testosterone prolactin Rattus norvegicus
2 When cultures containing both FSH + testosterone were treated with prolactin, progesterone secretion by cells from proestrous rats was significantly enhanced, whereas secretion by cells from HPX rats was significantly depressed. Testosterone prolactin Rattus norvegicus
3 Therefore when cells from HPX rats were cultured with both FSH and testosterone, the direction of the effect of prolactin was reversed from that observed with prolactin + FSH or testosterone alone, and from that observed when cells from proestrous rats were cultured with prolactin + FSH + testosterone. Testosterone prolactin Rattus norvegicus
4 Therefore when cells from HPX rats were cultured with both FSH and testosterone, the direction of the effect of prolactin was reversed from that observed with prolactin + FSH or testosterone alone, and from that observed when cells from proestrous rats were cultured with prolactin + FSH + testosterone. Testosterone prolactin Rattus norvegicus
5 Therefore when cells from HPX rats were cultured with both FSH and testosterone, the direction of the effect of prolactin was reversed from that observed with prolactin + FSH or testosterone alone, and from that observed when cells from proestrous rats were cultured with prolactin + FSH + testosterone. Testosterone prolactin Rattus norvegicus