Title : Hypercholesterolemia in young adult APOE-/- mice alters epidermal lipid composition and impairs barrier function.

Pub. Date : 2019 Jul

PMID : 30905828






2 Functional Relationships(s)
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1 Interestingly, the free fatty acid profile in the APOE-/- epidermis shifted towards shorter and unsaturated chains. Fatty Acids apolipoprotein E Mus musculus
2 Genes involved in the synthesis of cholesterol and fatty acids were downregulated in APOE-/- skin suggesting a compensation for the higher influx of plasma lipids, most probably as cholesteryl esters. Fatty Acids apolipoprotein E Mus musculus