Title : Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.

Pub. Date : 2019 Mar 21

PMID : 30899002






1 Functional Relationships(s)
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1 Here we demonstrate that Rb and mTORC1 contribute to Gln-addiction upon the dysregulation of the Fbxo4-cyclin D1 axis, which leads to the reprogramming of cellular metabolism. Glutamine cyclin D1 Homo sapiens