Pub. Date : 2019 Mar 14
PMID : 30875717
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Effect of Green and Black Tea Polyphenols on BRCA2 Deficient Chinese Hamster Cells by Synthetic Lethality through PARP Inhibition. | Polyphenols | poly [ADP-ribose] polymerase 1 | Cricetulus griseus |
| 2 | The observed cytotoxicity of these polyphenols to BRCA2 deficient cells is believed to be a result of PARP inhibition induced synthetic lethality. | Polyphenols | poly [ADP-ribose] polymerase 1 | Cricetulus griseus |
| 3 | In conclusion, tea polyphenols, epigallocatechin gallate, and theaflavin may present selective cytotoxicity to BRCA2 deficient cells through synthetic lethality induced by PARP inhibition. | Polyphenols | poly [ADP-ribose] polymerase 1 | Cricetulus griseus |