Pub. Date : 2019 Mar
PMID : 30841462
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We observed changes in microRNAs and aryl hydrocarbon receptor (AhR) as potential biomarkers in triptolide-induced acute cardiotoxicity by using techniques such as polymerase chain reaction (PCR) assay. | triptolide | aryl hydrocarbon receptor | Rattus norvegicus |
| 2 | We observed changes in microRNAs and aryl hydrocarbon receptor (AhR) as potential biomarkers in triptolide-induced acute cardiotoxicity by using techniques such as polymerase chain reaction (PCR) assay. | triptolide | aryl hydrocarbon receptor | Rattus norvegicus |
| 3 | Moreover, triptolide reduced the circulatory and cardiac levels of AhR protein as a target of these microRNAs and the messenger RNA expression of its downstream gene CYP1 A1. | triptolide | aryl hydrocarbon receptor | Rattus norvegicus |
| 4 | These results revealed that circulating microRNAs and AhR protein are potentially early-warning biomarkers for triptolide-induced cardiotoxicity. | triptolide | aryl hydrocarbon receptor | Rattus norvegicus |