Title : Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

Pub. Date : 2019 Apr

PMID : 30833751






1 Functional Relationships(s)
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1 Biochemical analysis demonstrates that QPCTL is critical for pyroglutamate formation on CD47 at the SIRPalpha binding site shortly after biosynthesis. Pyrrolidonecarboxylic Acid leukocyte surface antigen CD47 Cricetulus griseus