Title : Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria.

Pub. Date : 2019 Apr 1

PMID : 30830789






1 Functional Relationships(s)
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1 We conclude that although milk could enhance the solubilization of poorly water-soluble OZ439 during in vitro digestion principally due to the formation of fatty acids, the solubilization efficiency was reduced by the presence of FQ by competition for the available fatty acids. Fatty Acids Weaning weight-maternal milk Bos taurus