Title : Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells.

Pub. Date : 2019 May

PMID : 30825616






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Combination of canertinib and Pd(II) complex promotes autophagy and apoptosis of HeLa cancer cells via blockade of the PI3K/AKT and MAPK/ERK pathway, which leads to cervical cancer cell death. poly-4-dioxan-2-one AKT serine/threonine kinase 1 Homo sapiens
2 CONCLUSION: Inhibition of EGFR signaling by canertinib in combination with Pd(II) complex promotes apoptosis and autophagy via blockade of the PI3K/AKT and MAPK/ERK. poly-4-dioxan-2-one AKT serine/threonine kinase 1 Homo sapiens