Pub. Date : 2019 Jun
PMID : 30825187
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non-small cell lung cancer cells via Nrf2 inhibition. | diosmetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | Diosmetin induced ROS production in NSCLC cells probably via reducing Nrf2 stability through disruption of the PI3K/Akt/GSK-3beta pathway. | diosmetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 3 | CONCLUSIONS AND IMPLICATIONS: Diosmetin selectively induced apoptosis and enhanced the efficacy of paclitaxel in NSCLC cells via ROS accumulation through disruption of the PI3K/Akt/GSK-3beta/Nrf2 pathway. | diosmetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |