Pub. Date : 2019
PMID : 30814984
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Taxonomic Distribution of FosB in Human-Microbiota and Activity Comparison of Fosfomycin Resistance. | Fosfomycin | FosB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | FosB, a Mg2+ dependent thioltransferase, confers antibiotic resistance to fosfomycin through enzymatic drug inactivation. | Fosfomycin | FosB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Finally, we confirmed that FosB from the group of Staphylococcus presented the highest resistance ability to fosfomycin by in silico and in vitro comparisons. | Fosfomycin | FosB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 4 | In summary, this study elaborates the specific taxonomic characteristics and resistant abilities of FosB in human microbiota, which might help in developing more promising fosfomycin-like antibiotics. | Fosfomycin | FosB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |