Title : Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia.

Pub. Date : 2019 Feb 27

PMID : 30813936






1 Functional Relationships(s)
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1 CONCLUSIONS: The delay in DSB repair and lower sensitivity to daunorubicin seen in the B lymphocyte derived SUP-B15 cells could be due to loss of function of p53 that may be correlated to increased expression of SOD2 and lower ROS production. Daunorubicin tumor protein p53 Homo sapiens