Title : Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia.

Pub. Date : 2019 Feb 27

PMID : 30813936






1 Functional Relationships(s)
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1 CONCLUSIONS: The delay in DSB repair and lower sensitivity to daunorubicin seen in the B lymphocyte derived SUP-B15 cells could be due to loss of function of p53 that may be correlated to increased expression of SOD2 and lower ROS production. Reactive Oxygen Species tumor protein p53 Homo sapiens