Title : Tyramine action on motoneuron excitability and adaptable tyramine/octopamine ratios adjust Drosophila locomotion to nutritional state.

Pub. Date : 2019 Feb 26

PMID : 30808766






3 Functional Relationships(s)
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1 We further show that the level of tyramine-beta-hydroxylase (TBH), the enzyme that converts tyramine into octopamine in aminergic neurons, is increased by food deprivation, thus selecting between antagonistic amine actions on motoneurons. Octopamine Tyramine beta hydroxylase Drosophila melanogaster
2 We further show that the level of tyramine-beta-hydroxylase (TBH), the enzyme that converts tyramine into octopamine in aminergic neurons, is increased by food deprivation, thus selecting between antagonistic amine actions on motoneurons. Octopamine Tyramine beta hydroxylase Drosophila melanogaster
3 Therefore, octopamine and tyramine provide global but distinctly different mechanisms to regulate motoneuron excitability and behavioral plasticity, and their antagonistic actions are balanced within a dynamic range by nutritional effects on TBH. Octopamine Tyramine beta hydroxylase Drosophila melanogaster