Title : Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity.

Pub. Date : 2019 Jun 1

PMID : 30796443






2 Functional Relationships(s)
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1 Also, caspase-2 and caspase-3 inhibitors effectively blocked endosulfan-induced apoptotic cell death. Endosulfan caspase 3 Homo sapiens
2 CRISPR/Cas9-based stable knockdown of PKCdelta significantly attenuated endosulfan-induced caspase-3 activation, indicating that the kinase serves as a regulatory switch for apoptosis. Endosulfan caspase 3 Homo sapiens