Title : Purification and Characterization of Human Niemann-Pick C1 Protein.

Pub. Date : 2019

PMID : 30790261






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Niemann-Pick C1 (NPC1) is a membrane protein required for the transport of low-density lipoprotein (LDL)-derived cholesterol from endosomes and lysosomes to the other organelles. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
2 Niemann-Pick C1 (NPC1) is a membrane protein required for the transport of low-density lipoprotein (LDL)-derived cholesterol from endosomes and lysosomes to the other organelles. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
3 Finally, we also describe two biochemical approaches to characterize NPC1 function in vitro-a cholesterol transfer assay from purified NPC2 to NPC1 and a binding assay between NPC1 and NPC2. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens